There are two extremes to worry about. One is the extreme in which everything is known and there’s nothing left to do. The other is where everything is so complicated you can never begin to do anything. We are lucky to live in a universe were there are laws of nature and things to discover, but they’re not impossibly difficult, so we can understand them to some extent. But they’re also difficult enough so that we’re nowhere near understanding them all. There are exhilarating discoveries yet to be made. It’s the best possible world.
Human knowledge is a set of successive approximations. There are all sorts of things that we’ve gotten wrong, and all sorts of mind-boggling things that we can’t even glimpse that will be the established fact in a century or two.
We are bathing in mystery and confusion on many subjects, and I think that will always be our destiny. The universe will always be much richer than our ability to understand it.
Carl Sagan